Quick Search:

uzh logo
Browse by:

Zurich Open Repository and Archive

Maintenance: Tuesday, 5.7.2016, 07:00-08:00

Maintenance work on ZORA and JDB on Tuesday, 5th July, 07h00-08h00. During this time there will be a brief unavailability for about 1 hour. Please be patient.

Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-50273

Fujiwara, J; Tobler, Philippe N; Taira, M; Iijima, T; Tsutsui, K I (2008). Personality-dependent dissociation of absolute and relative loss processing in orbitofrontal cortex. European Journal of Neuroscience, 27(6):1547-1552.

[img]Published Version
PDF - Registered users only
View at publisher


A negative outcome can have motivational and emotional consequences on its own (absolute loss) or in comparison to alternative, better, outcomes (relative loss). The consequences of incurring a loss are moderated by personality factors such as neuroticism and introversion. However, the neuronal basis of this moderation is unknown. Here we investigated the neuronal basis of loss processing and personality with functional magnetic resonance imaging in a choice task. We separated absolute and relative financial loss by sequentially revealing the chosen and unchosen outcomes. With increasing neuroticism, activity in the left lateral orbitofrontal cortex (OFC) preferentially reflected relative rather than absolute losses. Conversely, with increasing introversion, activity in the right lateral OFC preferentially reflected absolute rather than relative losses. These results suggest that personality affects loss-related processing through the lateral OFC, and propose a dissociation of personality dimension and loss type on the neuronal level.


10 citations in Web of Science®
10 citations in Scopus®
Google Scholar™



15 downloads since deposited on 27 Oct 2011
2 downloads since 12 months

Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:03 Faculty of Economics > Department of Economics
08 University Research Priority Programs > Foundations of Human Social Behavior: Altruism and Egoism
Dewey Decimal Classification:170 Ethics
330 Economics
Deposited On:27 Oct 2011 14:25
Last Modified:05 Apr 2016 15:03
ISSN:0953-816X (P) 1460-9568 (E)
Additional Information:The attached file is a preprint (accepted version) of an article published in The European journal of neuroscience“
Publisher DOI:10.1111/j.1460-9568.2008.06096.x
PubMed ID:18336572

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page