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L1CAM protein expression is associated with poor prognosis in non-small cell lung cancer


Tischler, V; Pfeifer, M; Hausladen, S; Schirmer, U; Bonde, A K; Kristiansen, G; Sos, M L; Weder, W; Moch, H; Altevogt, P; Soltermann, A (2011). L1CAM protein expression is associated with poor prognosis in non-small cell lung cancer. Molecular Cancer, 10:127.

Abstract

A subset of NSCLCs with vessel tropism and increased metastasis aberrantly expresses L1CAM. L1CAM is a novel prognostic marker for NSCLCs that is upregulated by EMT induction and appears to be instrumental for enhanced cell invasion.

A subset of NSCLCs with vessel tropism and increased metastasis aberrantly expresses L1CAM. L1CAM is a novel prognostic marker for NSCLCs that is upregulated by EMT induction and appears to be instrumental for enhanced cell invasion.

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29 citations in Web of Science®
31 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Institute of Surgical Pathology
04 Faculty of Medicine > University Hospital Zurich > Clinic for Thoracic Surgery
Dewey Decimal Classification:610 Medicine & health
Language:German
Date:2011
Deposited On:28 Oct 2011 09:24
Last Modified:05 Apr 2016 15:03
Publisher:BioMed Central
ISSN:1476-4598
Publisher DOI:10.1186/1476-4598-10-127
PubMed ID:21985405
Permanent URL: http://doi.org/10.5167/uzh-50368

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