Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-50513
Schittenhelm, J; Simon, P; Harter, P N; Zachskorn, C; Schlaszus, H; Röttger, F; Winkels, M; Weller, M; Meyermann, R; Mittelbronn, M (2011). CD133 expression is associated with small round blue cell tumour morphology in human central nervous system neoplasms. Histopathology, 58(5):739-749.
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Abstract
CD133 expression in human CNS neoplasms is independent of the grade of malignancy but strongly correlates with SRBCT morphology. Together with recent findings showing that CD133 is quickly upregulated upon hypoxia and that CD133(-) cells can also exhibit stem cell properties, our data strongly question the suitability of CD133 as a brain tumour stem cell marker in vivo.
| Item Type: | Journal Article, refereed, original work |
|---|---|
| Communities & Collections: | 04 Faculty of Medicine > University Hospital Zurich > Clinic for Neurology |
| DDC: | 610 Medicine & health |
| Language: | English |
| Date: | 2011 |
| Deposited On: | 04 Nov 2011 09:24 |
| Last Modified: | 06 Dec 2012 06:15 |
| Publisher: | Wiley-Blackwell |
| ISSN: | 0309-0167 |
| Publisher DOI: | 10.1111/j.1365-2559.2011.03801.x |
| PubMed ID: | 21438906 |
| WoS Citation Count: | 3 |
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