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A functional variant of the serotonin transporter gene (SLC6A4) moderates impulsive choice in attention-deficit/hyperactivity disorder boys and siblings


Sonuga-Barke, E J S; Kumsta, R; Schlotz, W; Lasky-Su, J; Marco, R; Miranda, A; Mulas, F; Oades, R D; Banaschewski, T; Mueller, U; Andreou, P; Christiansen, H; Gabriels, I; Uebel, H; Kuntsi, J; Franke, B; Buitelaar, J; Ebstein, R; Gill, M; Anney, R; Roeyers, H; Rothenberger, A; Sergeant, J; Steinhausen, H C; Asherson, P; Faraone, S V (2011). A functional variant of the serotonin transporter gene (SLC6A4) moderates impulsive choice in attention-deficit/hyperactivity disorder boys and siblings. Biological Psychiatry, 70(3):230-236.

Abstract

The results support the genetic distinctiveness of IDIR and delay aversion in ADHD and implicate serotonin function in delay aversion. Possible explanations of the heterosis effect in the ADHD cases are presented.

The results support the genetic distinctiveness of IDIR and delay aversion in ADHD and implicate serotonin function in delay aversion. Possible explanations of the heterosis effect in the ADHD cases are presented.

Citations

22 citations in Web of Science®
24 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Center for Child and Adolescent Psychiatry
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:September 2011
Deposited On:04 Nov 2011 07:43
Last Modified:05 Apr 2016 15:04
Publisher:Elsevier
ISSN:0006-3223
Publisher DOI:https://doi.org/10.1016/j.biopsych.2011.01.040
PubMed ID:21497794

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