Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-519
Steinmann-Zwicky, M (1993). Sex determination in Drosophila: sis-b, a major numerator element of the X:A ratio in the soma, does not contribute to the X:A ratio in the germ line. Development, 117(2):763-767.
In soma and germ cells of Drosophila, the X:A ratio builds a primary signal for sex determination, and in both tissues Sex-lethal (Sxl) function is required for cells to enter the female pathway. In somatic cells of XX animals, the products of X-chromosomal elements of the X:A ratio activate Sxl. Here I show that sisterless-b (sis-b), which is the X-chromosomal element of the somatic X:A ratio that has best been analysed, is not required for oogenesis. I also present evidence that Sxl function might not be sufficient to direct germ cells into the female pathway. These results show that the elements forming the X:A ratio in the germ line are different from the elements forming the X:A ratio in the soma and they suggest that, in the germ line, Sxl might not be regulated by the X:A ratio.
|Item Type:||Journal Article, refereed|
|Communities & Collections:||07 Faculty of Science > Institute of Molecular Life Sciences|
|DDC:||570 Life sciences; biology|
|Date:||1 February 1993|
|Deposited On:||11 Feb 2008 12:15|
|Last Modified:||27 Nov 2013 16:41|
|Publisher:||Company of Biologists|
|Citations:||Web of Science®. Times Cited: 38|
Scopus®. Citation Count: 24
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