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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-5268

Eloranta, J J; Kullak-Ublick, G A (2008). The role of FXR in disorders of bile acid homeostasis. Physiology, 23:286-295.

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As ligands for the nuclear receptor FXR, bile acids regulate their own synthesis, transport, and conjugation, thus protecting against bile acid toxicity. Recently, the role of genetic variants in FXR itself, FXR target genes, and regulators of FXR in the pathophysiology of the liver and intestine has become increasingly evident.


43 citations in Web of Science®
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3 downloads since deposited on 11 Nov 2008
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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Clinical Pharmacology and Toxicology
04 Faculty of Medicine > Center for Integrative Human Physiology
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Deposited On:11 Nov 2008 07:47
Last Modified:05 Apr 2016 12:33
Publisher:American Physiological Society
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:10.1152/physiol.00020.2008
PubMed ID:18927204

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