Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-52924
Haerle, S K; Soyka, M B; Schmid, D T; Ahmad, N; Huber, G F; Crook, D W; Hany, T F (2012). Improved treatment outcomes with (18) F-FDG PET/CT for patients with advanced head and neck squamous cell carcinoma. Head & neck, 34(9):1205-1211.
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BACKGROUND: The aim of this study was to assess the impact of (18) F-fluoro-2-deoxy-D-glucose ((18) F-FDG) PET/CT on survival for patients with head and neck squamous cell carcinoma correlated with a matched patient cohort. METHODS: In all, disease in 58 patients was initially staged using (18) F-FDG PET/CT. A case-control analysis was done with 63 patients who disease was staged without (18) F-FDG-PET/CT. RESULTS: Disease-specific survival (DSS) and overall survival (OS) did not show significant differences between both groups. Statistical analysis revealed no difference in DSS and OS between the 2 groups for patients treated by radiochemotherapy (p = .975 and p = .671). In the analysis of survival in patients treated by a combined approach (surgery + radiochemotherapy), a significant difference in favor of patients evaluated by (18) F-FDG PET/CT was found (p = .05 and p = .027). CONCLUSIONS: Addition of (18) F-FDG PET/CT in patients treated by surgery and conformal radiochemotherapy improves outcome. This may be due to the more comprehensive topographic orientation of the primary tumor for the surgeon. © 2011 Wiley Periodicals, Inc. Head Neck, 2011.
|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||04 Faculty of Medicine > University Hospital Zurich > Clinic for Otorhinolaryngology|
04 Faculty of Medicine > University Hospital Zurich > Clinic for Nuclear Medicine
|DDC:||610 Medicine & health|
|Deposited On:||09 Dec 2011 14:30|
|Last Modified:||03 Dec 2012 21:30|
|Free access at:||Official URL. An embargo period may apply.|
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