Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-52933
Hlushchuk, R; Ehrbar, M; Reichmuth, P; Heinimann, N; Styp-Rekowska, B; Escher, R; Baum, O; Lienemann, P; Makanya, A; Keshet, E; Djonov, V (2011). Decrease in VEGF expression induces intussusceptive vascular pruning. Arteriosclerosis, Thrombosis, and Vascular Biology, 31(12):2836-2844.
View at publisher
Diminution of VEGF level induces vascular tree regression by intussusceptive vascular pruning. This observation may allude to the mechanism underlying the "normalization" of tumor vasculature if treated with antiangiogenic drugs. The mechanism described here gives new insights into the understanding of the processes of vasculature regression and hence provides new and potentially viable targets for antiangiogenic and/or angio-modulating therapies during various pathological processes.
99 downloads since deposited on 06 Jan 2012
39 downloads since 12 months
|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||04 Faculty of Medicine > University Hospital Zurich > Clinic for Obstetrics|
|Dewey Decimal Classification:||610 Medicine & health|
|Deposited On:||06 Jan 2012 13:11|
|Last Modified:||02 Dec 2013 20:25|
|Publisher:||Lippincott Wiliams & Wilkins|
Users (please log in): suggest update or correction for this item
Repository Staff Only: item control page