Quick Search:

uzh logo
Browse by:

The deadline for the annual report 2015 is January 31st, 2016

Zurich Open Repository and Archive

Maintenance: Tuesday, 16.2.2015, 06:00-08:00

Maintenance work on various system components of ZORA. During this time there will be a brief unavailability for about 1 hour. Please be patient.

Yonekawa, K; Neidhart, M; Altwegg, L A; Wyss, C A; Corti, R; Vogl, T; Grigorian, M; Gay, S; Lüscher, T F; Maier, W (2011). Myeloid related proteins activate toll-like receptor 4 in human acute coronary syndromes. Atherosclerosis, 218(2):486-492.

Full text not available from this repository.

View at publisher


In ACS, MRP8 and MRP8/14 complex are specific ligands of TLR4, which induce the release of TNFα and probably other pro-inflammatory agents from monocytes. This specific MRP8/14-dependent pathway with striking similarities to sepsis increasing expression of TLR4 in thrombi appears to be involved in the pathogenesis of coronary occlusion and may represent a novel therapeutic target in ACS.


26 citations in Web of Science®
27 citations in Scopus®
Google Scholar™


Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Rheumatology Clinic and Institute of Physical Medicine
04 Faculty of Medicine > University Hospital Zurich > Clinic for Cardiology
Dewey Decimal Classification:610 Medicine & health
Deposited On:06 Jan 2012 14:20
Last Modified:27 Nov 2013 19:15
Publisher DOI:10.1016/j.atherosclerosis.2011.06.020
PubMed ID:21782178

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page