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Single plasmonic nanoparticles for biosensing


Sannomiya, T; Vörös, J (2011). Single plasmonic nanoparticles for biosensing. Trends in Biotechnology, 29(7):343-351.

Abstract

Along with remarkable progress of nanoplasmonics over the past 10years, single plasmonic nanoparticle sensors have introduced a completely new dimension to the sensing scale, considering that nanoparticles are comparable in size to biomolecules such as nucleic acids or antibodies. Single particle sensing methods have recently shown the possibility of detecting the adsorption of single biomolecules, and have already provided information about conformational changes of single molecules. For practical application, arrays of such compact sensor units are expected to realize massive multiplexing and high throughput in diagnostics and drug discovery in the near future. In this review, recent achievements and perspectives of this emerging biosensing technique are discussed.

Along with remarkable progress of nanoplasmonics over the past 10years, single plasmonic nanoparticle sensors have introduced a completely new dimension to the sensing scale, considering that nanoparticles are comparable in size to biomolecules such as nucleic acids or antibodies. Single particle sensing methods have recently shown the possibility of detecting the adsorption of single biomolecules, and have already provided information about conformational changes of single molecules. For practical application, arrays of such compact sensor units are expected to realize massive multiplexing and high throughput in diagnostics and drug discovery in the near future. In this review, recent achievements and perspectives of this emerging biosensing technique are discussed.

Citations

45 citations in Web of Science®
47 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Biomedical Engineering
Dewey Decimal Classification:170 Ethics
610 Medicine & health
Language:English
Date:2011
Deposited On:13 Jan 2012 10:13
Last Modified:05 Apr 2016 15:17
Publisher:Elsevier
ISSN:0167-7799
Publisher DOI:https://doi.org/10.1016/j.tibtech.2011.03.003

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