Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-54186
Hofer, M; Schmid, C; Benden, C; Speich, R; Inci, I; Weder, W; Boehler, A (2012). Diabetes mellitus and survival in cystic fibrosis patients after lung transplantation. Journal of Cystic Fibrosis, 11(2):131-136.
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BACKGROUND: Diabetes mellitus (DM) is common in CF and associated with more severe disease. It is unclear whether DM influences outcome of lung transplantation (LTx). METHODS: One hundred twenty-three CF patients evaluated for LTx at our centre were included. Survival was calculated. RESULTS: Patients with and without DM did not differ with regard to gender, age, FEV(1) and BMI prior to LTx. Eighty patients (65%) had a diagnosis of DM before and 13 (11%) only after LTx. Recipients with DM had a significantly higher 1- and 5-year survival (89% and 71%) than those without (71% and 51%). In the multivariate Cox-regression analysis, DM had no impact on LTx-survival. CONCLUSIONS: One- and five-year survival rates after LTx tend to be better in CF recipients with DM compared to those without DM. No impact of DM on the development of BOS was found.
|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||04 Faculty of Medicine > University Hospital Zurich > Clinic and Policlinic for Internal Medicine|
04 Faculty of Medicine > University Hospital Zurich > Clinic for Pneumology
04 Faculty of Medicine > University Hospital Zurich > Clinic for Endocrinology and Diabetology
|DDC:||610 Medicine & health|
|Deposited On:||13 Jan 2012 21:15|
|Last Modified:||06 Feb 2013 21:38|
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