Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-55963
Armulik, A; Genové, G; Betsholtz, C (2011). Pericytes: developmental, physiological, and pathological perspectives, problems, and promises. Developmental Cell, 21(2):193-215.
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Pericytes, the mural cells of blood microvessels, have recently come into focus as regulators of vascular morphogenesis and function during development, cardiovascular homeostasis, and disease. Pericytes are implicated in the development of diabetic retinopathy and tissue fibrosis, and they are potential stromal targets for cancer therapy. Some pericytes are probably mesenchymal stem or progenitor cells, which give rise to adipocytes, cartilage, bone, and muscle. However, there is still confusion about the identity, ontogeny, and progeny of pericytes. Here, we review the history of these investigations, indicate emerging concepts, and point out problems and promise in the field of pericyte biology.
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|Item Type:||Journal Article, refereed, further contribution|
|Communities & Collections:||04 Faculty of Medicine > University Hospital Zurich > Institute of Neuropathology|
|DDC:||570 Life sciences; biology
610 Medicine & health
|Deposited On:||22 Jan 2012 16:41|
|Last Modified:||04 Dec 2013 01:45|
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