Quick Search:

uzh logo
Browse by:
bullet
bullet
bullet
bullet

Zurich Open Repository and Archive

Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-56438

van Lier, A L H M W; Brunner, D O; Pruessmann, K P; Klomp, D W J; Luijten, P R; Lagendijk, J J W; van den Berg, C A T (2011). B 1+ Phase mapping at 7 T and its application for in vivo electrical conductivity mapping. Magnetic Resonance in Medicine, 67(2):552-561.

[img]Published Version
PDF (Article in press) - Registered users only
1MB

View at publisher

Abstract

In this study, a new approach to measure local electrical conductivity in tissue is presented, which is based on the propagating B 1+ phase and the homogeneous Helmholtz equation. This new MRI technique might open future opportunities for tumor and lesion characterization based on conductivity differences, while it may also find application in radio frequency safety assessment. Prerequisites for conductivity mapping using only the B 1+ phase (instead of the complex B +1 field) are addressed. Furthermore it was found that the B 1+ phase can be derived directly from the measurable transceive phase arg(B +1 B -1) in the head. Validation for a human head excited by a 7 T-birdcage coil using simulations and measurements showed that it is possible to measure in vivo conductivity patterns in the brain using B 1+ phase information only. Conductivity contrast between different brain tissues is clearly observed. The measured mean values for white matter, gray matter and cerebrospinal fluid differed 54%, 26%, and -13% respectively from literature values. The proposed method for B 1+ phase measurements is very suited for in vivo applications, as the measurement is short (less than a minute per imaged slice) and exposes the patient to low RF power, contrary to earlier proposed approaches. Magn Reson Med, 2011. © 2011 Wiley-Liss, Inc.

Citations

19 citations in Web of Science®
16 citations in Scopus®
Google Scholar™

Altmetrics

Downloads

1 download since deposited on 22 Jan 2012
0 downloads since 12 months

Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Biomedical Engineering
DDC:170 Ethics
610 Medicine & health
Language:English
Date:2011
Deposited On:22 Jan 2012 20:38
Last Modified:03 Jan 2014 16:48
Publisher:Wiley-Blackwell
ISSN:0740-3194
Publisher DOI:10.1002/mrm.22995
PubMed ID:21710613

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page