Quick Search:

uzh logo
Browse by:

Zurich Open Repository and Archive

Maintenance: Tuesday, July the 26th 2016, 07:00-10:00

ZORA's new graphical user interface will be relaunched (For further infos watch out slideshow ZORA: Neues Look & Feel). There will be short interrupts on ZORA Service between 07:00am and 10:00 am. Please be patient.

Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-56463

Kyriakou, A; Neufeld, E; Szczerba, D; Kainz, W; Luechinger, R; Kozerke, S; McGregor, R; Kuster, N (2012). Patient-specific simulations and measurements of the magneto-hemodynamic effect in human primary vessels. Physiological Measurement, 33(2):117-130.

[img]Published Version
PDF - Registered users only
View at publisher


This paper investigates the main characteristics of the magneto-hemodynamic (MHD) response for application as a biomarker of vascular blood flow. The induced surface potential changes of a volunteer exposed to a 3 T static B0 field of a magnetic resonance imaging (MRI) magnet were measured over time at multiple locations by an electrocardiogram device and compared to simulation results. The flow simulations were based on boundary conditions derived from MRI flow measurements restricted to the aorta and vena cava. A dedicated and validated low-frequency electromagnetic solver was applied to determine the induced temporal surface potential change from the obtained 4D flow distribution using a detailed whole-body model of the volunteer. The simulated MHD signal agreed with major characteristics of the measured signal (temporal location of main peak, magnitude, variation across chest and along torso) except in the vicinity of the heart. The MHD signal is mostly influenced by the aorta; however, more vessels and better boundary conditions are needed to analyze the finer details of the response. The results show that the MHD signal is strongly position dependent with highly variable but reproducibly measurable distinguished characteristics. Additional investigations are necessary before determining whether the MHD effect is a reliable reference for location-specific information on blood flow.


8 citations in Web of Science®
8 citations in Scopus®
Google Scholar™



2 downloads since deposited on 30 Mar 2012
0 downloads since 12 months

Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Biomedical Engineering
Dewey Decimal Classification:170 Ethics
610 Medicine & health
Deposited On:30 Mar 2012 07:56
Last Modified:05 Apr 2016 15:27
Publisher:Institute of Physics Publishing
Publisher DOI:10.1088/0967-3334/33/2/117
PubMed ID:22227810

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page