Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-56869
Mloston, G; Pieczonka, A M; Korany, A A; Linden, A; Heimgartner, H (2012). A new approach to morpholin-2-one derivatives via the reaction of β-amino alcohols with dicyanofumarates. ARKIVOC, 2012(iii):181-192.
|Published Version (English)|
A novel approach for the synthesis of morpholin-2-one derivatives from dialkyl dicyanofumarates and β-amino alcohols is presented. The reaction takes place under mild conditions via an addition-elimination-lactonization pathway. The formation of the six- membered ring occurs selectively leading to a single diastereomer. In contrast to arylhydrazines, the reaction of hydrazine hydrate with dicyanofumarates yields pyrazol-3(2H)-ones and not 5-aminopyrazoles.
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|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||07 Faculty of Science > Department of Chemistry|
|Date:||23 January 2012|
|Deposited On:||02 Apr 2012 07:20|
|Last Modified:||10 Jul 2014 21:13|
|Publisher:||Arkat USA Inc|
|Funders:||European Social Fund ‘HUMAN – BEST INVESTMENT!’|
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