Westheide, J; Quednow, B B; Kühn, K U; Hoppe, C; Cooper-Mahkorn, D; Hawellek, B; Eichler, P; Maier, W; Wagner, M (2008). Executive performance of depressed suicide attempters: the role of suicidal ideation. European Archives of Psychiatry and Clinical Neuroscience, 258(7):414-421.
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Abstract
OBJECTIVE: Suicidal ideation has been related to cognitive rigidity whereas suicidal behaviour itself was associated with specific executive deficits. Yet it remains unclear if a distinct cognitive suicidal phenotype does exist. The aim of the present study was to further investigate the role of suicidal thinking for the neuropsychological performance in depressive suicide attempters. METHOD: Depressive inpatients after a recent suicide attempt, who either had present suicidal ideation (n = 14) or not (n = 15) and healthy controls (n = 29) were recruited. The groups were assessed by means of executive tasks designed to capture impulsive decision-making, and with verbal memory and attention tests. Self-rating measures of impulsivity and aggression were further applied. RESULTS: Only patients with current suicidal ideation showed executive dysfunctions with impaired decision-making being the most salient. Verbal memory and attention were reasonably intact in all patients. All patients reported increased aggression. CONCLUSION: Suicidal ideation is clearly associated with impaired cognitive performance. Our results suggest that executive deficits seen in depressive suicide attempters have a state-dependent component.
| Item Type: | Journal Article, refereed, original work |
|---|---|
| Communities & Collections: | 04 Faculty of Medicine > Psychiatric University Hospital Zurich > Clinic for Psychiatry, Psychotherapy, and Psychosomatics |
| DDC: | 610 Medicine & health |
| Language: | English |
| Date: | October 2008 |
| Deposited On: | 20 Nov 2008 10:45 |
| Last Modified: | 23 Nov 2012 17:08 |
| Publisher: | Springer |
| ISSN: | 0940-1334 |
| Additional Information: | The original publication is available at www.springerlink.com |
| Publisher DOI: | 10.1007/s00406-008-0811-1 |
| PubMed ID: | 18330667 |
| WoS Citation Count: | 15 |
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