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Westheide, J; Quednow, B B; Kühn, K U; Hoppe, C; Cooper-Mahkorn, D; Hawellek, B; Eichler, P; Maier, W; Wagner, M (2008). Executive performance of depressed suicide attempters: the role of suicidal ideation. European Archives of Psychiatry and Clinical Neuroscience, 258(7):414-421.

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Abstract

OBJECTIVE: Suicidal ideation has been related to cognitive rigidity whereas suicidal behaviour itself was associated with specific executive deficits. Yet it remains unclear if a distinct cognitive suicidal phenotype does exist. The aim of the present study was to further investigate the role of suicidal thinking for the neuropsychological performance in depressive suicide attempters. METHOD: Depressive inpatients after a recent suicide attempt, who either had present suicidal ideation (n = 14) or not (n = 15) and healthy controls (n = 29) were recruited. The groups were assessed by means of executive tasks designed to capture impulsive decision-making, and with verbal memory and attention tests. Self-rating measures of impulsivity and aggression were further applied. RESULTS: Only patients with current suicidal ideation showed executive dysfunctions with impaired decision-making being the most salient. Verbal memory and attention were reasonably intact in all patients. All patients reported increased aggression. CONCLUSION: Suicidal ideation is clearly associated with impaired cognitive performance. Our results suggest that executive deficits seen in depressive suicide attempters have a state-dependent component.

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Psychiatric University Hospital Zurich > Clinic for Psychiatry, Psychotherapy, and Psychosomatics
DDC:610 Medicine & health
Language:English
Date:October 2008
Deposited On:20 Nov 2008 10:45
Last Modified:27 Nov 2013 19:33
Publisher:Springer
ISSN:0940-1334
Additional Information:The original publication is available at www.springerlink.com
Publisher DOI:10.1007/s00406-008-0811-1
PubMed ID:18330667
Citations:Web of Science®. Times Cited: 21
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