Quick Search:

uzh logo
Browse by:

Zurich Open Repository and Archive

Maintenance: Tuesday, July the 26th 2016, 07:00-10:00

ZORA's new graphical user interface will be relaunched (For further infos watch out slideshow ZORA: Neues Look & Feel). There will be short interrupts on ZORA Service between 07:00am and 10:00 am. Please be patient.

Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-57591

Kelly, B J; Diefenbach, E; Fraefel, C; Diefenbach, R J (2012). Identification of host cell proteins which interact with herpes simplex virus type 1 tegument protein pUL37. Biochemical and Biophysical Research Communications (BBRC), 417(3):961-965.

[img]Published Version
PDF - Registered users only
View at publisher


The herpes simplex virus type 1 (HSV-1) structural tegument protein pUL37, which is conserved across the Herpesviridae family, is known to be essential for secondary envelopment during the egress of viral particles. To shed light on additional roles of pUL37 during viral replication a yeast two-hybrid screen of a human brain cDNA library was undertaken. This screen identified ten host cell proteins as potential pUL37 interactors. One of the interactors, serine threonine kinase TAOK3, was subsequently confirmed to interact with pUL37 using an in vitro pulldown assay. Such host cell/pUL37 interactions provide further insights into the multifunctional role of this herpesviral tegument protein.


5 citations in Web of Science®
5 citations in Scopus®
Google Scholar™



5 downloads since deposited on 02 Mar 2012
0 downloads since 12 months

Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Institute of Virology
Dewey Decimal Classification:570 Life sciences; biology
Date:19 December 2012
Deposited On:02 Mar 2012 12:52
Last Modified:05 Apr 2016 15:31
Publisher DOI:10.1016/j.bbrc.2011.12.044
PubMed ID:22202175

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page