Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-57600
Dummer, R; Goldinger, S M; Cozzio, A; French, L E; Karpova, M B (2012). Cutaneous lymphomas: Molecular pathways leading to new drugs. Journal of Investigative Dermatology, 132(3):517-525.
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Currently, cutaneous lymphomas represent a paradigm for the heterogeneity and the dynamic variability of neoplastic disorders resulting in the accumulation of clonal lymphocytes in the skin, and thus mirror the complexity of lymphocytic populations. Increasing knowledge and insight in pathobiology offer new opportunities for targeted interventions to selectively hit the tumor populations. mAbs, rexinoids, small kinase inhibitors, or molecules interfering with methylation or histone acetylation contribute to disease control. The rational and well-coordinated application of these tools, together with improved chemotherapeutic options, will hopefully further improve treatment success in the near future.Journal of Investigative Dermatology advance online publication, 8 December 2011; doi:10.1038/jid.2011.370.
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|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||04 Faculty of Medicine > University Hospital Zurich > Dermatology Clinic|
|DDC:||610 Medicine & health|
|Deposited On:||02 Feb 2012 20:27|
|Last Modified:||12 Dec 2013 19:38|
|Publisher:||Nature Publishing Group|
|ISSN:||0022-202X (P) 1523-1747 (E)|
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