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Impaired cerebral autoregulation using near-infrared spectroscopy and its relation to clinical outcomes in premature infants


Caicedo, A; De Smet, D; Vanderhaegen, J; Naulaers, G; Wolf, M; Lemmers, P; Van Bel, F; Ameye, L; Van Huffel, S (2011). Impaired cerebral autoregulation using near-infrared spectroscopy and its relation to clinical outcomes in premature infants. In: LaManna, J C; Puchowicz, M A; Xu, K; Harrison, D K; Bruley, D F. Oxygen transport to tissue XXXII. New York: Springer, 233-239.

Abstract

The concordance between the change in the Mean Arterial Blood Pressure (MABP) and the Cerebral Blood Flow (CBF) is studied using the Correlation, Coherence and Partial Coherence methods in order to detect Impaired Cerebral Autoregulation in Neonates. The presence of impaired autoregulation is assessed by the use of the Critical Percentage of Recording Time (CPRT). The changes in CBF are reflected by the measurement of changes in cerebral intravascular oxygenation (HbD), regional cerebral oxygen saturation (rSO(2)), and cerebral tissue oxygenation (TOI), as measured by Near-Infrared Spectroscopy (NIRS) (INVOS4100 and NIRO300). The relation between impaired autoregulation and long term clinical outcomes in premature infants is studied.

The concordance between the change in the Mean Arterial Blood Pressure (MABP) and the Cerebral Blood Flow (CBF) is studied using the Correlation, Coherence and Partial Coherence methods in order to detect Impaired Cerebral Autoregulation in Neonates. The presence of impaired autoregulation is assessed by the use of the Critical Percentage of Recording Time (CPRT). The changes in CBF are reflected by the measurement of changes in cerebral intravascular oxygenation (HbD), regional cerebral oxygen saturation (rSO(2)), and cerebral tissue oxygenation (TOI), as measured by Near-Infrared Spectroscopy (NIRS) (INVOS4100 and NIRO300). The relation between impaired autoregulation and long term clinical outcomes in premature infants is studied.

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Additional indexing

Item Type:Book Section, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Neonatology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2011
Deposited On:10 Feb 2012 20:48
Last Modified:05 Apr 2016 15:31
Publisher:Springer
Series Name:Advances in Experimental Medicine and Biology
Number:701, Pt 8
ISSN:0065-2598
ISBN:978-1-4419-7755-7 (hbk.) 978-1-4419-7756-4 (e-ISBN)
Additional Information:Conference proceedings, 37th annual ISOTT Conference, 2009, Cleveland, Ohio, USA
Publisher DOI:10.1007/978-1-4419-7756-4_31
Related URLs:http://opac.nebis.ch/F/?local_base=NEBIS&CON_LNG=GER&func=find-b&find_code=SYS&request=006493527
PubMed ID:21445792
Permanent URL: http://doi.org/10.5167/uzh-57648

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