Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-58111
Wong, W. Wei-Lynn; Silke, J (2009). Another Facet of Ubiquitylation: Death. Journal of Molecular Cell Biology, 1(2):80-81.
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Abstract
Ubiquitylation of caspase-8 by the Cullin3 E3 ligase allows its translocation to cytosolic aggregates in the cell by p62/sequesto- some-1, increasing caspase-8 activation and thus leading to TRAIL-induced cell death.
| Item Type: | Journal Article, refereed, further contribution |
|---|---|
| Communities & Collections: | 04 Faculty of Medicine > University Hospital Zurich > Institute of Experimental Immunology |
| DDC: | 570 Life sciences; biology 610 Medicine & health |
| Language: | English |
| Date: | 2009 |
| Deposited On: | 15 Jun 2012 17:35 |
| Last Modified: | 06 May 2013 01:20 |
| Publisher: | Oxford University Press |
| ISSN: | 1759-4685 |
| Free access at: | Publisher DOI. An embargo period may apply. |
| Publisher DOI: | 10.1093/jmcb/mjp019 |
| PubMed ID: | 19797318 |
| WoS Citation Count: | 0 |
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