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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-5874

Cuculi, F; Radovanovic, D; Eberli, F R; Stauffer, J C; Bertel, O; Erne, P; AMIS Plus Investigators, (2008). The impact of statin treatment on presentation mode and early outcomes in acute coronary syndromes. Cardiology, 109(3):156-162.

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Abstract

Objectives: The role of statin use in the treatment of acute coronary syndromes (ACS) is not clear. The aim of our study was to evaluate the role of statins in ACS. Methods: Using data from the Acute Myocardial Infarction in Switzerland (AMIS Plus) Project, we compared the effects of chronic statin use, statin therapy after admission and no statin therapy on presentation mode and outcomes in ACS. Results: Available data from the period 2001-2006 including 11,603 patients were analyzed. Major cardiac event rates and in-hospital mortality were more common in statin-naive patients compared to patients who received statins. Conclusions: Our results support the importance of statin treatment in ACS. Chronic statin therapy seems to alter the initial presentation of ACS but it is questionable whether it provides an additional effect on early outcomes compared to the establishment of statin therapy after admission in statin-naive patients.

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8 citations in Web of Science®
11 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Epidemology, Biostatistics and Prevention Institute (EBPI)
DDC:610 Medicine & health
Language:English
Date:2008
Deposited On:25 Nov 2008 09:57
Last Modified:27 Nov 2013 19:02
Publisher:Karger
ISSN:0008-6312
Publisher DOI:10.1159/000106676
Official URL:http://dx.doi.org/10.1159/000106676

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