Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-59406
Lucke, Katja; Hombach, Michael; Friedel, Ute; Ritter, Claudia; Böttger, Erik C (2012). Automated quantitative drug susceptibility testing of non-tuberculous mycobacteria using MGIT 960/EpiCenter TB eXiST. Journal of Antimicrobial Chemotherapy, 67(1):154-158.
PDF - Registered users only
View at publisher
OBJECTIVES: To assess the predictive value of in vitro drug susceptibility testing (DST) in slow-growing non-tuberculous mycobacteria (NTM), knowledge on quantitative levels of drug susceptibility should be available. The aim of this study was to investigate the suitability of the MGIT 960/TB eXiST system for quantitative DST of NTM. METHODS: We have assessed quantitative levels of drug susceptibility for clinical isolates of Mycobacterium avium, Mycobacterium intracellulare and Mycobacterium kansasii by comparing radiometric Bactec 460TB-based DST with non-radiometric DST using MGIT 960/TB eXiST. RESULTS: MGIT 960/TB eXiST gives results comparable to those of Bactec 460TB. CONCLUSIONS: The MGIT 960/TB eXiST appears suitable for quantitative DST of NTM.
0 downloads since deposited on 03 Apr 2012
0 downloads since 12 months
|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||04 Faculty of Medicine > Institute of Medical Microbiology|
|Dewey Decimal Classification:||570 Life sciences; biology
610 Medicine & health
|Deposited On:||03 Apr 2012 09:01|
|Last Modified:||20 Jan 2014 05:10|
|Publisher:||Oxford University Press|
Users (please log in): suggest update or correction for this item
Repository Staff Only: item control page