Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-59799
Gloy, V; Langhans, W; Hillebrand, J J; Geary, N; Asarian, L (2011). Ovariectomy and overeating palatable, energy-dense food increase subcutaneous adipose tissue more than intra-abdominal adipose tissue in rats. Biology of Sex Difference, 2:6.
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Both ovariectomy in rats and menopause are associated with increased TAT. After ovariectomy, fat is preferentially deposited as SAT and lean body mass increases, whereas after menopause fat is preferentially deposited as IAAT and lean body mass decreases. These opposite effects of ovariectomy and menopause on regional AT distribution and lean body mass indicate that ovariectomy in rats is not a homologous model of menopause-associated changes in body composition that should be used with great caution in investigations of adiposity-related diseases.
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|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||05 Vetsuisse Faculty > Institute of Veterinary Physiology|
|Dewey Decimal Classification:||570 Life sciences; biology|
|Deposited On:||17 Mar 2012 19:19|
|Last Modified:||01 Dec 2012 07:21|
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