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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-59920

Sigel, R K O; Freisinger, E; Abbate, M; Lippert, B (2002). Hydrogen bonding patterns of 7,9-dimethylguanine and its transplatinum(II) complexes. Inorganica Chimica Acta, 339:355-365.

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Abstract

Methylation at the N7 position is one of the most frequently naturally occurring modifications of guanosine. This alteration drastically changes the hydrogen bonding and acid–base properties of the guanine nucleobase. Here we show on the example of the model nucleobase 7,9-dimethylguanine that due to blockage of N7 of the purine ring, new hydrogen bonding patterns occur on the minor groove binding face of this nucleobase involving the ring nitrogen N3 and the exocyclic amino group N2H2. The free 7,9-dimethylguaninium ion and several transplatinum(II) complexes of the this ligand are presented and discussed.

Item Type:Journal Article, refereed, original work
Communities & Collections:07 Faculty of Science > Institute of Inorganic Chemistry
DDC:540 Chemistry
Language:English
Date:2002
Deposited On:27 Jun 2012 13:25
Last Modified:29 Nov 2013 12:24
Publisher:Elsevier
ISSN:0020-1693
Publisher DOI:10.1016/S0020-1693(02)00962-3
Citations:Web of Science®. Times Cited: 13
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