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Kamarashev, J A; Kaddu, S (2011). Non-melanoma skin cancer: Appendageal tumours. In: Dummer, R; Pittelkow, M R; Iwatsuki, K; Green, A; Elwan, N M. Skin cancer - a world-wide perspective. Heidelberg, DE, 121-167. ISBN 978-3-642-05071-8 (P) 978-3-642-05072-5 (E).

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Abstract

Sudoriferous tumours represent approximately 1% of all primary cutaneous neoplasias. They have a variable, often unspecific clinical presentation and a wide histologic spectrum. According to their origin, cutaneous sweat gland tumours can be classified as eccrine, apocrine, eccrine and apocrine (mixed origin), or composite adnexal tumours. Further, they can be classified as benign or malignant, tumours of the sweat ducts or of the sweat glands secretory apparatus. Carcinomas of the eccrine and apocrine glands are neoplasms with infiltrative and metastatic potential. Some malignancies have benign counterparts from which they must be differentiated. Features that suggest malignancy include asymmetry of the lesion, invasion, irregular arrangement of neoplastic cells, cytonuclear atypia and pleomorphism, and significantly increased mitotic activity in the presence of abnormal mitotic figures. Other sweat gland carcinomas present differently from any benign tumour. Differentiating primary cutaneous sudoriferous carcinomas from metastatic carcinomas can often pose a serious challenge. Clinical history, histomorphological features, and immunohistochemical stains are all very important.

Item Type:Book Section, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Dermatology Clinic
DDC:610 Medicine & health
Language:English
Date:2011
Deposited On:11 Mar 2012 19:43
Last Modified:04 Apr 2012 16:24
Publisher:Springer
ISBN:978-3-642-05071-8 (P) 978-3-642-05072-5 (E)
Publisher DOI:10.1007/978-3-642-05072-5_16
Related URLs:http://opac.nebis.ch/F/?local_base=NEBIS&CON_LNG=GER&func=find-b&find_code=SYS&request=006410635
Citations:Google Scholarā„¢

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