Abstract

Cutaneous lymphomas, like other lymphomas, are systemic diseases by definition. Therefore, surgery has limited indications. However, primary cutaneous B-cell lymphomas (CBCL), such as follicle center lymphomas and large cell primary cutaneous CD30+ T-cell lymphomas, may present as a single nodule in the skin. In these cases, because investigation on tumor material is necessary, an excision biopsy might be a good alternative to an incisional biopsy. In the case of surgical treatment of a nodule in primary cutaneous lymphomas, a safety margin of at least 1 cm should be applied, although there are no supporting clinical trails.