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Cheyne-stokes respiration in patients with heart failure: prevalence, causes, consequences and treatments


Brack, Thomas; Randerath, Winfried; Bloch, Konrad E (2012). Cheyne-stokes respiration in patients with heart failure: prevalence, causes, consequences and treatments. Respiration, 83(2):165-176.

Abstract

Cheyne-Stokes respiration (CSR) is characterized by a pattern of cyclic oscillations of tidal volume and respiratory rate with periods of hyperpnea alternating with hypopnea or apnea in patients with heart failure. CSR harms the failing heart through intermittent hypoxia brought about by apnea and hypopnea and recurrent sympathetic surges. CSR impairs the quality of life and increases cardiac mortality in patients with heart failure. Thus, CSR should actively be pursued in patients with severe heart failure. When CSR persists despite optimal therapy of heart failure, noninvasive adaptive servoventilation is currently the most promising treatment.

Cheyne-Stokes respiration (CSR) is characterized by a pattern of cyclic oscillations of tidal volume and respiratory rate with periods of hyperpnea alternating with hypopnea or apnea in patients with heart failure. CSR harms the failing heart through intermittent hypoxia brought about by apnea and hypopnea and recurrent sympathetic surges. CSR impairs the quality of life and increases cardiac mortality in patients with heart failure. Thus, CSR should actively be pursued in patients with severe heart failure. When CSR persists despite optimal therapy of heart failure, noninvasive adaptive servoventilation is currently the most promising treatment.

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14 citations in Web of Science®
17 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Pneumology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2012
Deposited On:05 Apr 2012 13:09
Last Modified:15 Jun 2016 15:55
Publisher:Karger
ISSN:0025-7931
Additional Information:© 2012 S. Karger AG
Publisher DOI:10.1159/000331457
PubMed ID:22025128
Permanent URL: http://doi.org/10.5167/uzh-60146

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