Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-60446
Käppeli, U; Hächler, H; Giezendanner, N; Cheasty, T; Stephan, R (2011). Shiga toxin-producing Escherichia coli O157 associated with human infections in Switzerland, 2000-2009. Epidemiology and Infection, 139(7):1097-1104.
SUMMARY: Shiga toxin-producing Escherichia coli (STEC), an important foodborne pathogen, can cause mild to severe bloody diarrhoea (BD), sometimes followed by life-threatening complications such as haemolytic uraemic syndrome (HUS). A total of 44 O157 strains isolated from different patients from 2000 through 2009 in Switzerland were further characterized and linked to medical history data. Non-bloody diarrhoea was experienced by 15·9%, BD by 61·4% of the patients, and 29·5% developed HUS. All strains belonged to MLST type 11, were positive for stx2 variants (stx2 and/or stx2c), eae and ehxA, and only two strains showed antibiotic resistance. Of the 44 strains, nine phage types (PTs) were detected the most frequent being PT32 (43·2%) and PT8 (18·2%). By PFGE, 39 different patterns were found. This high genetic diversity within the strains leads to the conclusion that STEC O157 infections in Switzerland most often occur as sporadic cases.
|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||05 Vetsuisse Faculty > Institute of Food Safety and Hygiene|
|DDC:||570 Life sciences; biology|
610 Medicine & health
|Deposited On:||17 Mar 2012 21:15|
|Last Modified:||26 Nov 2012 11:29|
|Publisher:||Cambridge University Press|
|Additional Information:||Copyright: Cambridge University Press.|
|Other Identification Number:||20875198|
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