Quick Search:

uzh logo
Browse by:

Zurich Open Repository and Archive

Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-60446

Käppeli, U; Hächler, H; Giezendanner, N; Cheasty, T; Stephan, R (2011). Shiga toxin-producing Escherichia coli O157 associated with human infections in Switzerland, 2000-2009. Epidemiology and Infection, 139(7):1097-1104.

Published Version

View at publisher


SUMMARY: Shiga toxin-producing Escherichia coli (STEC), an important foodborne pathogen, can cause mild to severe bloody diarrhoea (BD), sometimes followed by life-threatening complications such as haemolytic uraemic syndrome (HUS). A total of 44 O157 strains isolated from different patients from 2000 through 2009 in Switzerland were further characterized and linked to medical history data. Non-bloody diarrhoea was experienced by 15·9%, BD by 61·4% of the patients, and 29·5% developed HUS. All strains belonged to MLST type 11, were positive for stx2 variants (stx2 and/or stx2c), eae and ehxA, and only two strains showed antibiotic resistance. Of the 44 strains, nine phage types (PTs) were detected the most frequent being PT32 (43·2%) and PT8 (18·2%). By PFGE, 39 different patterns were found. This high genetic diversity within the strains leads to the conclusion that STEC O157 infections in Switzerland most often occur as sporadic cases.


9 citations in Web of Science®
8 citations in Scopus®
Google Scholar™



25 downloads since deposited on 17 Mar 2012
4 downloads since 12 months

Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Institute of Food Safety and Hygiene
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Deposited On:17 Mar 2012 20:15
Last Modified:15 Dec 2013 20:18
Publisher:Cambridge University Press
Additional Information:Copyright: Cambridge University Press.
Publisher DOI:10.1017/S0950268810002190
Other Identification Number:20875198

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page