Quick Search:

uzh logo
Browse by:
bullet
bullet
bullet
bullet

Zurich Open Repository and Archive 

Lesku, J A; Vyssotski, A L; Martinez-Gonzalez, D; Wilzeck, C; Rattenborg, N C (2011). Local sleep homeostasis in the avian brain. Proceedings of the Royal Society B: Biological Sciences, 278(1717):2419-2428.

Full text not available from this repository.

Abstract

The function of the brain activity that defines slow wave sleep (SWS) and rapid eye movement (REM) sleep in mammals is unknown. During SWS, the level of electroencephalogram slow wave activity (SWA or 0.5-4.5 Hz power density) increases and decreases as a function of prior time spent awake and asleep, respectively. Such dynamics occur in response to waking brain use, as SWA increases locally in brain regions used more extensively during prior wakefulness. Thus, SWA is thought to reflect homeostatically regulated processes potentially tied to maintaining optimal brain functioning. Interestingly, birds also engage in SWS and REM sleep, a similarity that arose via convergent evolution, as sleeping reptiles and amphibians do not show similar brain activity. Although birds deprived of sleep show global increases in SWA during subsequent sleep, it is unclear whether avian sleep is likewise regulated locally. Here, we provide, to our knowledge, the first electrophysiological evidence for local sleep homeostasis in the avian brain. After staying awake watching David Attenborough's The Life of Birds with only one eye, SWA and the slope of slow waves (a purported marker of synaptic strength) increased only in the hyperpallium-a primary visual processing region-neurologically connected to the stimulated eye. Asymmetries were specific to the hyperpallium, as the non-visual mesopallium showed a symmetric increase in SWA and wave slope. Thus, hypotheses for the function of mammalian SWS that rely on local sleep homeostasis may apply also to birds.

Item Type:Journal Article, refereed, original work
Communities & Collections:07 Faculty of Science > Institute of Neuroinformatics
DDC:570 Life sciences; biology
Uncontrolled Keywords:Potentiation;Slow wave activity;Synaptic downscaling;Synaptic strength
Language:English
Date:1 August 2011
Deposited On:05 Mar 2012 16:04
Last Modified:27 Nov 2013 23:44
Publisher:Royal Society of London
ISSN:0962-8452
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:10.1098/rspb.2010.2316
PubMed ID:21208955
Citations:Web of Science®. Times Cited: 13
Google Scholar™
Scopus®. Citation Count: 12

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page