Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-60730
Baumgartner, Markus R; Guglielmello, Rosetta; Fanger, Monique; Kraemer, Thomas (2012). Analysis of drugs of abuse in hair: Evaluation of the immunochemical method VMA-T vs. LC-MS/MS or GC-MS. Forensic Science International, 215(1-3):56-59.
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Hair analysis is an elaborate and time-consuming multi-step process. The immunometric test VMA-T from Comedical has been evaluated as screening assay for hair analysis. From routine work, authentic samples were selected that were positive for opiates, cocaine, MDMA-type drugs, amphetamines, methadone or THC. These hair samples were investigated by LC-MS or GC-MS and the VMA-T procedure, respectively. Using the cut-off values recommended by the Society of Hair Testing, the VMA-T method discriminates with good sensitivity between negative and positive hair samples and is an expedient screening method for drugs in keratinized matrices such as hair. In order to save time and resources, the residue of the VMA-T extraction solution can be reused for confirmation analysis by LC-MS except for cocaine.
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|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||04 Faculty of Medicine > Institute of Legal Medicine|
610 Medicine & health
|Deposited On:||10 Apr 2012 07:46|
|Last Modified:||01 Dec 2013 02:06|
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