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Lungentransplantation - wann muss in der Praxis daran gedacht werden


Hofer, M; Boehler, A (2011). Lungentransplantation - wann muss in der Praxis daran gedacht werden. Therapeutische Umschau, 68(12):725-729.

Abstract

To date, lung transplantation is an established therapeutic modality for advanced lung disease. Post-transplant survival is excellent, but depends on sophisticated medical follow-up and treatment by a dedicated and experienced multidisciplinary lung transplant team. Transplantation leads to markedly improved quality of life. Medical complications after lung transplantation are frequent, such as infections (viral, bacterial and fungal), gastro-esophageal reflux, osteoporosis and chronic rejection. Prevention of these complications is crucial and lifelong adherence to therapy is warranted. The most important hurdle in transplantation medicine to date is the marked shortage of donor organs making it impossible to transplant all patients in need. Living donation and ex vivo reconditioning of marginal lungs might bring some relief.

Zusammenfassung:

Die Lungentransplantation ist heute eine etablierte Therapie für fortgeschrittene Lungenkrankheiten. Die Ansprüche der posttransplantären Behandlung an das Transplantationsteam, die Patienten und deren Angehörige sind nach wie vor hoch. Eine enge medizinische Betreuung im spezialisierten Transplantationszentrum führt zu guten Resultaten. Gerade bei Lungenkrankheiten ohne medikamentöse Therapieoption wie der Lungenfibrose, sollte eine Überweisung ans Transplantationszentrum frühzeitig erfolgen.

Abstract

To date, lung transplantation is an established therapeutic modality for advanced lung disease. Post-transplant survival is excellent, but depends on sophisticated medical follow-up and treatment by a dedicated and experienced multidisciplinary lung transplant team. Transplantation leads to markedly improved quality of life. Medical complications after lung transplantation are frequent, such as infections (viral, bacterial and fungal), gastro-esophageal reflux, osteoporosis and chronic rejection. Prevention of these complications is crucial and lifelong adherence to therapy is warranted. The most important hurdle in transplantation medicine to date is the marked shortage of donor organs making it impossible to transplant all patients in need. Living donation and ex vivo reconditioning of marginal lungs might bring some relief.

Zusammenfassung:

Die Lungentransplantation ist heute eine etablierte Therapie für fortgeschrittene Lungenkrankheiten. Die Ansprüche der posttransplantären Behandlung an das Transplantationsteam, die Patienten und deren Angehörige sind nach wie vor hoch. Eine enge medizinische Betreuung im spezialisierten Transplantationszentrum führt zu guten Resultaten. Gerade bei Lungenkrankheiten ohne medikamentöse Therapieoption wie der Lungenfibrose, sollte eine Überweisung ans Transplantationszentrum frühzeitig erfolgen.

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Additional indexing

Other titles:Lung transplantation and patient evaluation
Item Type:Journal Article, not refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Pneumology
Dewey Decimal Classification:610 Medicine & health
Language:German
Date:2011
Deposited On:03 Mar 2012 12:47
Last Modified:05 Apr 2016 15:43
Publisher:Hans Huber
ISSN:0040-5930
Publisher DOI:https://doi.org/10.1024/0040-5930/a000236
Related URLs:http://www.verlag-hanshuber.com/zeitschriften/journal.php?abbrev=TUM&show=abstract&abstract=33126
PubMed ID:22139988

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