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Ras--a versatile cellular switch.


Rommel, C; Hafen, E (1998). Ras--a versatile cellular switch. Current Opinion in Genetics & Development, 8(4):412-418.

Abstract

With the number of known roles played by Ras proteins increasing rapidly, finding answers to how the diverse cellular responses are triggered is becoming increasingly pertinent. Although our understanding of the control of specificity of signal transduction is still small, the combination of biochemical, structural and genetic analyses is starting to reveal how the cell-specific responses to Ras activation are controlled.

With the number of known roles played by Ras proteins increasing rapidly, finding answers to how the diverse cellular responses are triggered is becoming increasingly pertinent. Although our understanding of the control of specificity of signal transduction is still small, the combination of biochemical, structural and genetic analyses is starting to reveal how the cell-specific responses to Ras activation are controlled.

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84 citations in Web of Science®
92 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed
Communities & Collections:07 Faculty of Science > Institute of Zoology (former)
Dewey Decimal Classification:570 Life sciences; biology
590 Animals (Zoology)
Language:English
Date:1 August 1998
Deposited On:11 Feb 2008 12:16
Last Modified:05 Apr 2016 12:15
Publisher:Elsevier
ISSN:0959-437X
Publisher DOI:10.1016/S0959-437X(98)80111-1
PubMed ID:9729716

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