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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-62141

Barnes, T S; Deplazes, P; Gottstein, B; Jenkins, D J; Mathis, A; Siles-Lucas, M; Torgerson, P R; Ziadinov, I; Heath , D D (2012). Challenges for diagnosis and control of cystic hydatid disease. Acta Tropica, 123(1):1-7.

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Abstract

This paper is based on the experience of the authors, with the aim to define the challenges for Echinococcus granulosus (E.g./CE) diagnosis and control for those countries that may now or in the future be contemplating control of hydatid disease. A variety of methods are available for diagnosis in humans but a universal gold standard is lacking. Diagnosis in definitive hosts can avoid necropsy by the use of methods such as coproantigen detection but test performance is variable between populations. A sylvatic cycle adds challenges in some countries and the epidemiology of the parasite in these hosts is poorly understood. Control by solely administering praziquantel to dogs is not effective in developing countries where the disease is endemic. Additional avenues to pursue include the instigation of participatory planning, use of an existing vaccination for intermediate hosts and development of a vaccine and long-acting anthelmitic implants for definitive hosts. Promoting public acceptance of control of the dog population by humane euthanasia and reduced reproduction is also essential.

Item Type:Journal Article, refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Institute of Parasitology
04 Faculty of Medicine > Institute of Parasitology

05 Vetsuisse Faculty > Chair in Veterinary Epidemiology
DDC:570 Life sciences; biology
610 Medicine & health
600 Technology
Language:English
Date:2012
Deposited On:09 May 2012 07:14
Last Modified:24 Dec 2013 22:51
Publisher:Elsevier
ISSN:0001-706X
Publisher DOI:10.1016/j.actatropica.2012.02.066
PubMed ID:22410539
Citations:Web of Science®. Times Cited: 10
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Scopus®. Citation Count: 12

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