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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-6229

Zuber, M; Cuculi, F; Oechslin, E; Erne, P; Jenni, R (2008). Is transesophageal echocardiography still necessary to exclude patent foramen ovale? Scandinavian Cardiovascular Journal : SCJ, 42(3):222-225.

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OBJECTIVES: Current guidelines still recommend transesophageal echocardiography (TEE) as reference method to diagnose interatrial shunts. The aim was to test the accuracy of high-end transthoracal echocardiography (TTE) to exclude inter-atrial shunts. METHODS: Prospective TTE and TEE study with second harmonic imaging to determine left-to-right shunt (L/R) by both colour Doppler or R/L by contrast echocardiography in patients with unexplained cerebrovascular incidents or newly detected valvular or myocardial disease. RESULTS: An inter-atrial shunt was diagnosed in 200 of 438 analyzed patients (117 males). Colour Doppler echocardiography visualized a shunt in 67 patients (34%) on TTE vs. 84 (42%) patients on TEE (p <0.0001). However injection of agitated blood with a valsalva maneuver detected 190 (95%) interatrial shunts by both TTE and TEE, but 10 shunts (5%) only by TTE. CONCLUSIONS: Our study shows that patent foramen ovale can safely be demonstrated with high-end transthoracic contrast- echocardiography. If additional studies confirm our results, TTE has the potential to become the method of choice in the diagnosis of PFO.


10 citations in Web of Science®
15 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Cardiology
Dewey Decimal Classification:610 Medicine & health
Date:June 2008
Deposited On:01 Dec 2008 14:26
Last Modified:05 Apr 2016 12:36
Publisher:Taylor & Francis
Additional Information:This is an electronic version of an article published in Scandinavian Cardiovascular Journal, Volume 42, Issue 3 2008 , pages 222 - 225. Is transesophageal echocardiography still necessary to exclude patent foramen ovale? is available online at DOI: 10.1080/14017430801932832
Publisher DOI:10.1080/14017430801932832
PubMed ID:18569955

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