Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-6263
Cattapan-Ludewig, K; Ludewig, S; Messerli, N; Vollenweider, F X; Seitz, A; Feldon, J; Paulus, M P (2008). Decision-making dysregulation in first-episode schizophrenia. Journal of Nervous and Mental Disease, 196(2):157-160.
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Studies with chronic schizophrenia patients have demonstrated that patients fluctuate between rigid and unpredictable responses in decision-making situations, a phenomenon which has been called dysregulation. The aim of this study was to investigate whether schizophrenia patients already display dysregulated behavior at the beginning of their illness. Thirty-two first-episode schizophrenia or schizophreniform patients and 30 healthy controls performed the two-choice prediction task. The decision-making behavior of first-episode patients was shown to be characterized by a high degree of dysregulation accompanied by low metric entropy and a tendency towards increased mutual information. These results indicate that behavioral abnormalities during the two-choice prediction task are already present during the early stages of the illness.
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|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||04 Faculty of Medicine > Psychiatric University Hospital Zurich > Clinic for Psychiatry, Psychotherapy, and Psychosomatics|
|DDC:||610 Medicine & health|
|Deposited On:||11 Dec 2008 23:04|
|Last Modified:||27 Nov 2013 19:39|
|Publisher:||Lippincott Wiliams & Wilkins|
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