Glacier- and permafrost-related hazards increasingly threaten human lives, settlements, and infrastructure in high-mountain regions. Present atmospheric warming particularly affects terrestrial systems where surface and sub-surface ice are involved. Changes in glacier and permafrost equilibrium are shifting beyond historical knowledge. Human settlement and activities are extending toward danger zones in the cryospheric system. A number of recent glacier hazards and disasters underscore these trends. Difficult site access and the need for fast data acquisition make satellite remote sensing of crucial importance in high-mountain hazard management and disaster mapping.