Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-6329
Hennet, T (2009). From glycosylation disorders back to glycosylation: what have we learned? Biochimica et Biophysica Acta, 1792(9):921-924.
Diseases of glycosylation have long remained confined to the rare hematological disorders, the Tn-syndrome  and paroxysmal nocturnal hemoglobinuria . This rarity was often interpreted as a sign that defects of glycosylation are either lethal, or remain asymptomatic because of the large redundancy found in glycosylation pathways. The description of multiple glycosylation disorders over the last years has definitively settled the issue and demonstrated the broad range of biological processes relying on proper glycosylation. However, beyond establishing the developmental and physiological roles of glycosylation how did glycosylation disorders contribute to new insights in the field of glycobiology?
|Item Type:||Journal Article, refereed, further contribution|
|Communities & Collections:||04 Faculty of Medicine > Center for Integrative Human Physiology|
04 Faculty of Medicine > Institute of Physiology
07 Faculty of Science > Institute of Physiology
|DDC:||570 Life sciences; biology|
610 Medicine & health
|Deposited On:||02 Dec 2008 13:31|
|Last Modified:||23 Nov 2012 16:39|
|WoS Citation Count:||3|
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