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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-63883

Bektas, R N; Kutter, A P N; Hartnack, S; Jud, R; Schnyder, M; Matos, J M; Bettschart-Wolfensberger, R (2012). Evaluation of a minimally invasive non-calibrated pulse contour cardiac output monitor (FloTrac/Vigileo) in anaesthetized dogs. Veterinary Anaesthesia and Analgesia, 39(5):464-471.

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Abstract

Objective  To evaluate the accuracy of a new cardiac output monitor (FloTrac/Vigileo), originally designed for humans, in dogs. This pulse contour cardiac output monitoring system cannot be calibrated and measures cardiac output (Q̇t) from a standard arterial catheter. Study design  Prospective experimental trial. Animals  Eight adult Beagle dogs weighing 13.1 (9.8-17.1) kg [median (range)]. Methods  Anaesthesia in the dogs was maintained using isoflurane. A pulmonary artery catheter and a metatarsal arterial catheter (22 gauge) were placed. Cardiac output was measured simultaneously 331 times by thermodilution and FloTrac technique. A broad spectrum of Q̇t measurements was achieved through alterations of isoflurane concentration, administration of propofol boluses and dobutamine infusions. Agreement between the methods was quantified with Bland Altman analysis and disagreement was assessed with linear mixed models. Results  Median (10th and 90th percentile) cardiac output as measured with thermodilution was 2.54 (1.47 and 5.15) L minute(-1) and as measured with FloTrac 8.6 (3.9 and 17.3) L minute(-1) . FloTrac measurements were consistently higher with a mean bias of 7 L minute(-1) and limits of agreement of -3.15 to 17.17 L minute(-1) . Difference between the methods was most pronounced in high Q̇t measurements. Linear mixed models showed an estimated difference between the two methods of 8.05 (standard error 1.18) L minute(-1) and a significant interaction between mean arterial pressure and method. Standard deviation (4.45 higher) with the FloTrac method compared to thermodilution was increased. Conclusion  Compared to thermodilution measurements, the FloTrac system was influenced to a higher degree by arterial blood pressure, resulting in consistent overestimation of cardiac output. Clinical Relevance  The FloTrac monitor, whose algorithms were developed based on human data, cannot be used as an alternative for thermodilution in dogs.

Item Type:Journal Article, refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Institute of Parasitology
04 Faculty of Medicine > Institute of Parasitology

05 Vetsuisse Faculty > Veterinary Clinic > Department of Small Animals > Clinic for Small Animal Internal Medicine
05 Vetsuisse Faculty > Chair in Veterinary Epidemiology
05 Vetsuisse Faculty > Veterinary Clinic > Equine Department > Equine Clinic
DDC:570 Life sciences; biology
610 Medicine & health
600 Technology
630 Agriculture
Language:English
Date:2012
Deposited On:26 Jul 2012 10:24
Last Modified:30 Nov 2013 02:53
Publisher:Wiley-Blackwell
ISSN:1467-2987
Publisher DOI:10.1111/j.1467-2995.2012.00741.x
Related URLs:http://www.zora.uzh.ch/59408/
PubMed ID:22726234
Citations:Web of Science®
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