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Fatal outcome after heart transplantation caused by Aspergillus lentulus


Zbinden, A; Imhof, A; Wilhelm, M J; Ruschitzka, F; Wild, P; Bloemberg, G V; Mueller, N J (2012). Fatal outcome after heart transplantation caused by Aspergillus lentulus. Transplant Infectious Disease, 14(5):E60-E63.

Abstract

Opportunistic invasive fungal infections are a major cause of mortality in immunocompromised patients. Early diagnosis of invasive aspergillosis and proper identification of the causative agent is crucial for guidance of therapy. Accurate differentiation of Aspergillus lentulus, a filamentous fungus often misidentified as atypical Aspergillus fumigatus, is of concern as multiple antifungal drugs show a reduced susceptibility. This is the first report, to our knowledge, of a proven pulmonary invasive fungal infection caused by A. lentulus after heart transplantation.

Opportunistic invasive fungal infections are a major cause of mortality in immunocompromised patients. Early diagnosis of invasive aspergillosis and proper identification of the causative agent is crucial for guidance of therapy. Accurate differentiation of Aspergillus lentulus, a filamentous fungus often misidentified as atypical Aspergillus fumigatus, is of concern as multiple antifungal drugs show a reduced susceptibility. This is the first report, to our knowledge, of a proven pulmonary invasive fungal infection caused by A. lentulus after heart transplantation.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Medical Microbiology
04 Faculty of Medicine > University Hospital Zurich > Clinic for Infectious Diseases
04 Faculty of Medicine > University Hospital Zurich > Clinic for Cardiovascular Surgery
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Language:English
Date:2012
Deposited On:25 Oct 2012 14:23
Last Modified:05 Apr 2016 16:01
Publisher:Wiley-Blackwell
ISSN:1398-2273
Publisher DOI:https://doi.org/10.1111/j.1399-3062.2012.00779.x
PubMed ID:22988985
Permanent URL: https://doi.org/10.5167/uzh-65868

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