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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-695

Burckhardt, C J; Greber, U F (2008). Redox rescues virus from ER trap. Nature Cell Biology, 10(1):9-11.

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Abstract

How viruses manage to resist physical and chemical stress and yet open their protective coats during cell infection has been a longstanding, fundamental question. A study with the DNA tumour virus SV40 now shows that protein folding and quality-control factors of the endoplasmic reticulum reshuffle disulfide bonds within the viral capsid, providing a molecular mechanism for the exit of infectious virions from the endoplasmic reticulum.

Item Type:Journal Article, refereed, further contribution
Communities & Collections:07 Faculty of Science > Institute of Molecular Life Sciences
DDC:570 Life sciences; biology
Language:English
Date:January 2008
Deposited On:11 Feb 2008 12:17
Last Modified:27 Nov 2013 22:49
Publisher:Nature Publishing Group
ISSN:1465-7392
Publisher DOI:10.1038/ncb0108-9
PubMed ID:18172426
Citations:Web of Science®. Times Cited: 5
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Scopus®. Citation Count: 5

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