Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-695
Burckhardt, C J; Greber, U F (2008). Redox rescues virus from ER trap. Nature Cell Biology, 10(1):9-11.
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| Accepted Version 357Kb |
Abstract
How viruses manage to resist physical and chemical stress and yet open their protective coats during cell infection has been a longstanding, fundamental question. A study with the DNA tumour virus SV40 now shows that protein folding and quality-control factors of the endoplasmic reticulum reshuffle disulfide bonds within the viral capsid, providing a molecular mechanism for the exit of infectious virions from the endoplasmic reticulum.
| Item Type: | Journal Article, refereed, further contribution |
|---|---|
| Communities & Collections: | 07 Faculty of Science > Institute of Molecular Life Sciences |
| DDC: | 570 Life sciences; biology |
| Language: | English |
| Date: | January 2008 |
| Deposited On: | 11 Feb 2008 13:17 |
| Last Modified: | 23 Nov 2012 14:42 |
| Publisher: | Nature Publishing Group |
| ISSN: | 1465-7392 |
| Publisher DOI: | 10.1038/ncb0108-9 |
| PubMed ID: | 18172426 |
| WoS Citation Count: | 4 |
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