Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-698
Zipperlen, P; Nairz, K; Rimann, I; Basler, K; Hafen, E; Hengartner, M; Hajnal, A (2005). A universal method for automated gene mapping. Genome Biology, 6(2):R19.
View at publisher
Small insertions or deletions (InDels) constitute a ubiquituous class of sequence polymorphisms found in eukaryotic genomes. Here, we present an automated high-throughput genotyping method that relies on the detection of fragment-length polymorphisms (FLPs) caused by InDels. The protocol utilizes standard sequencers and genotyping software. We have established genome-wide FLP maps for both Caenorhabditis elegans and Drosophila melanogaster that facilitate genetic mapping with a minimum of manual input and at comparatively low cost.
81 downloads since deposited on 11 Feb 2008
28 downloads since 12 months
|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||07 Faculty of Science > Institute of Molecular Life Sciences|
|Dewey Decimal Classification:||570 Life sciences; biology|
|Deposited On:||11 Feb 2008 12:17|
|Last Modified:||27 Nov 2013 19:48|
Users (please log in): suggest update or correction for this item
Repository Staff Only: item control page