Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-7143
Tappeiner, C; Barthelmes, D; Abegg, M H; Wolf, S; Fleischhauer, J C (2008). Impact of optic media opacities and image compression on quantitative analysis of optical coherence tomography. Investigative Ophthalmology and Visual Science, 49(4):1609-1614.
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PURPOSE: To analyze the impact of opacities in the optical pathway and image compression of 32-bit raw data to 8-bit jpg images on quantified optical coherence tomography (OCT) image analysis. METHODS: In 18 eyes of nine healthy subjects, OCT images were acquired from the central macula. To simulate opacities in the optical system, neutral-density (ND) filters with linear absorption spectra were placed between the OCT device and examined eyes. Light reflection profiles (LRPs) of images acquired with various ND filters were compared. LRPs of the 32-bit raw data were compared with those obtained from the 8-bit jpg compressed images. RESULTS: ND filters induced a linear decrease of reflectivity in OCT images, depending on initial signal intensity. Quantitative OCT analysis showed no significant difference between 32-bit raw data and 8-bit jpg files (P > 0.05). CONCLUSIONS: Quantitative OCT analysis is not significantly influenced by data compression. A mathematical model can correct for optical opacities to improve OCT images.
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|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||04 Faculty of Medicine > University Hospital Zurich > Ophthalmology Clinic|
|DDC:||610 Medicine & health|
|Date:||1 April 2008|
|Deposited On:||09 Dec 2008 15:04|
|Last Modified:||28 Nov 2013 00:58|
|Publisher:||Association for Research in Vision and Ophthalmology|
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