Quick Search:

uzh logo
Browse by:
bullet
bullet
bullet
bullet

Zurich Open Repository and Archive

Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-7150

Abegg, M; Tappeiner, C; Wolf-Schnurrbusch, U; Barthelmes, D; Wolf, S; Fleischhauer, J (2008). Treatment of branch retinal vein occlusion induced macular edema with bevacizumab. BMC Ophtalmology, 8:18:1-8.

[img]
Preview
PDF
3MB

View at publisher

Abstract

BACKGROUND: Branch retinal vein occlusion is a frequent cause of visual loss with currently insufficient treatment options. We evaluate the effect of Bevacizumab (Avastin) treatment in patients with macular edema induced by branch retinal vein occlusion. METHODS: Retrospective analysis of 32 eyes in 32 patients with fluorescein angiography proven branch retinal vein occlusion, macular edema and Bevacizumab treatment. Outcome measures were best corrected visual acuity in logMAR and central retinal thickness in OCT. RESULTS: Visual acuity was significantly better 4 to 6 weeks after Bevacizumab treatment compared to visual acuity prior to treatment (before 0.7 +/- 0.3 and after 0.5 +/- 0.3; mean +/- standard deviation; p < 0.01, paired t-test). Gain in visual acuity was accompanied by a significant decrease in retinal thickness (454 +/- 117 to 305 +/- 129 microm, p < 0.01, paired t-test). Follow up (170, 27 - 418 days; median, range) shows that improvement for both visual acuity and retinal thickness last for several months after Bevacizumab use. CONCLUSION: We present evidence that intravitreal Bevacizumab is an effective and lasting treatment for macular edema after branch retinal vein occlusion.

Citations

16 citations in Web of Science®
21 citations in Scopus®
Google Scholar™

Altmetrics

Downloads

229 downloads since deposited on 09 Dec 2008
72 downloads since 12 months

Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Ophthalmology Clinic
DDC:610 Medicine & health
Language:English
Date:29 September 2008
Deposited On:09 Dec 2008 08:02
Last Modified:27 Nov 2013 18:11
Publisher:BioMed Central
ISSN:1471-2415
Additional Information:Free full text article
Publisher DOI:10.1186/1471-2415-8-18
PubMed ID:18823536

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page