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Mesothelioma


Felley-Bosco, Emanuela; Opitz, Isabelle (2012). Mesothelioma. In: Stahel, Rolf A. Lung Cancer Therapy Annual 7. London: Informa Healthcare, 141-150.

Abstract

Malignant pleural mesothelioma (MPM) is a rare cancer mostly associated with asbestos exposure (reviewed in1) although very recently it has been found that germline mutations in BRCA1 associated protein-1 (BAP1) may predispose to mesothelioma development in non-asbestos exposed patients.2 The median latency between asbestos exposure and disease onset is 44.6 years based on the Italian Mesothelioma Registry and increases over time in a linear fashion.3 Environmental asbestos exposure is common in some villages of Turkey. Here the rate of mesothelioma mortality can be over hundred-fold higher than in control villages.

Abstract

Malignant pleural mesothelioma (MPM) is a rare cancer mostly associated with asbestos exposure (reviewed in1) although very recently it has been found that germline mutations in BRCA1 associated protein-1 (BAP1) may predispose to mesothelioma development in non-asbestos exposed patients.2 The median latency between asbestos exposure and disease onset is 44.6 years based on the Italian Mesothelioma Registry and increases over time in a linear fashion.3 Environmental asbestos exposure is common in some villages of Turkey. Here the rate of mesothelioma mortality can be over hundred-fold higher than in control villages.

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Additional indexing

Item Type:Book Section, not refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Division of Surgical Research
04 Faculty of Medicine > University Hospital Zurich > Clinic for Thoracic Surgery
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:July 2012
Deposited On:19 Feb 2013 13:09
Last Modified:05 Apr 2016 16:29
Publisher:Informa Healthcare
ISBN:978-1-8418-4865-5
Publisher DOI:https://doi.org/10.3109/9781841848679.013

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