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Microfluidic High-Throughput Screening


Maerkl, Sebastian J (2009). Microfluidic High-Throughput Screening. Integrative Biology, 1:19-29.

Abstract

Biology has always been a heavily technology limited field. Burgeoning fields such as systems biology require the development and implementation of new technologies, enabling high-throughput and high-fidelity measurements of large systems. Microfluidics promises to fulfil many of the requirements put forth. Here I will discuss the various approaches employed to date for performing high-throughput screening experiments on-chip, encompassing biochemical, biophysical, and cell-based assays.

Biology has always been a heavily technology limited field. Burgeoning fields such as systems biology require the development and implementation of new technologies, enabling high-throughput and high-fidelity measurements of large systems. Microfluidics promises to fulfil many of the requirements put forth. Here I will discuss the various approaches employed to date for performing high-throughput screening experiments on-chip, encompassing biochemical, biophysical, and cell-based assays.

Citations

20 citations in Web of Science®
19 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:Special Collections > SystemsX.ch
Special Collections > SystemsX.ch > Research, Technology and Development Projects > DynamiX
Special Collections > SystemsX.ch > Research, Technology and Development Projects
Dewey Decimal Classification:570 Life sciences; biology
Language:English
Date:2009
Deposited On:22 Jun 2013 14:18
Last Modified:05 Apr 2016 16:49
Publisher:RSC Publishing
ISSN:1757-9694
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:https://doi.org/10.1039/b819762h
Permanent URL: https://doi.org/10.5167/uzh-78705

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