Ramadan, K; Shevelev, I V; Hübscher, U (2004). The DNA-polymerase-X family: controllers of DNA quality? Nature Reviews. Molecular Cell Biology, 5(12):43.
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Abstract
Synthesis of the genetic material of the cell is achieved by a large number of DNA polymerases. Besides replicating the genome, they are involved in DNA-repair processes. Recent studies have indicated that certain DNA-polymerase-X-family members can synthesize unusual DNA structures, and we propose that these DNA structures might serve as 'flag wavers' for the induction of DNA-repair and/or DNA-damage-checkpoint pathways.
| Item Type: | Journal Article, refereed |
|---|---|
| Communities & Collections: | 05 Vetsuisse Faculty > Institute of Veterinary Biochemistry and Molecular Biology |
| DDC: | 570 Life sciences; biology |
| Language: | English |
| Date: | 01 December 2004 |
| Deposited On: | 11 Feb 2008 13:18 |
| Last Modified: | 23 Nov 2012 16:31 |
| Publisher: | Nature Publishing Group |
| ISSN: | 1471-0072 |
| Publisher DOI: | 10.1038/nrm1530 |
| PubMed ID: | 15573140 |
| WoS Citation Count: | 45 |
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