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Prosthetic valve endocarditis caused by Propionibacterium species successfully treated with coadministered rifampin: report of two cases


Braun, Dominique Laurent; Hasse, Barbara Katharina; Stricker, Julia; Fehr, Jan Sven (2013). Prosthetic valve endocarditis caused by Propionibacterium species successfully treated with coadministered rifampin: report of two cases. BMJ Case Reports, 2013:pii: bcr2012007204.

Abstract

We describe two cases of prosthetic valve endocarditis caused by Propionibacterium spp. successfully treated with a combination of rifampin and intravenous penicillin. Rifampin was chosen due to its promising activity against planktonic and biofilm Propionibacterium, its favourable minimal inhibitory concentrations, its excellent oral bioavailability and tissue penetration.

We describe two cases of prosthetic valve endocarditis caused by Propionibacterium spp. successfully treated with a combination of rifampin and intravenous penicillin. Rifampin was chosen due to its promising activity against planktonic and biofilm Propionibacterium, its favourable minimal inhibitory concentrations, its excellent oral bioavailability and tissue penetration.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Infectious Diseases
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2013
Deposited On:10 Oct 2013 12:05
Last Modified:05 Apr 2016 17:02
Publisher:BMJ Publishing Group
ISSN:1757-790X
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:https://doi.org/10.1136/bcr-2012-007204
PubMed ID:23355561

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