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Sudden death in a case of sickle cell anemia: Post-mortem computed tomography and autopsy correlation from a radiologist’s perspective


Abdul Rashid, S N; Krauskopf, A; Vonlanthen, B; Thali, M J; Ruder, T D (2013). Sudden death in a case of sickle cell anemia: Post-mortem computed tomography and autopsy correlation from a radiologist’s perspective. Legal Medicine, 15(4):213-216.

Abstract

Sickle cell anemia (SCA) is a hemolytic disease characterized by the production of abnormal hemoglobin chains and distorted red blood cell morphology or sickling. "Sickle cell crisis" includes vaso-occlusive crisis, a plastic crisis, sequestration crisis, haemolytic crisis and often culminating in serious complications, organ damage and even sudden death. Post-mortem computed tomography (PMCT) findings of sickle cell disease have never been reported in literature. This case of sudden death from acute hemolytic crisis in SCA where post-mortem computed tomography (PMCT) and autopsy findings complemented each other, both revealing findings invisible to the other and both crucial to the case.

Sickle cell anemia (SCA) is a hemolytic disease characterized by the production of abnormal hemoglobin chains and distorted red blood cell morphology or sickling. "Sickle cell crisis" includes vaso-occlusive crisis, a plastic crisis, sequestration crisis, haemolytic crisis and often culminating in serious complications, organ damage and even sudden death. Post-mortem computed tomography (PMCT) findings of sickle cell disease have never been reported in literature. This case of sudden death from acute hemolytic crisis in SCA where post-mortem computed tomography (PMCT) and autopsy findings complemented each other, both revealing findings invisible to the other and both crucial to the case.

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1 citation in Web of Science®
1 citation in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Legal Medicine
Dewey Decimal Classification:340 Law
610 Medicine & health
Language:English
Date:2013
Deposited On:24 Oct 2013 07:16
Last Modified:05 Apr 2016 17:04
Publisher:Elsevier
ISSN:1344-6223
Publisher DOI:https://doi.org/10.1016/j.legalmed.2013.01.003
PubMed ID:23453001

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