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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-835

Tasara, T; Hottiger, M O; Hübscher, U (2001). Functional genomics in HIV-1 virus replication: protein-protein interactions as a basis for recruiting the host cell machinery for viral propagation. Biological Chemistry, 382(7):993-999.



Identification and characterization of protein-protein interactions between the host cell and parasites both enhance our understanding of basic cell biology and provide insights into central processes of parasite life cycles. Research on HIV-1 has broadened our knowledge of the various molecular events involved. However, our understanding of how this virus interacts with the host cell at the level of protein-protein interaction is still limited. Through these interactions the virus is able to recruit certain cellular metabolic pathways for its replication. Here we summarize our current knowledge of protein-protein interactions between HIV-1 and host cell factors during viral replication.

Item Type:Journal Article, refereed
Communities & Collections:05 Vetsuisse Faculty > Institute of Veterinary Biochemistry and Molecular Biology
DDC:570 Life sciences; biology
Date:1 July 2001
Deposited On:11 Feb 2008 12:18
Last Modified:27 Nov 2013 20:10
Publisher:De Gruyter
Publisher DOI:10.1515/BC.2001.125
PubMed ID:11530943
Citations:Web of Science®. Times Cited: 7
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Scopus®. Citation Count: 8

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