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The role of bacterial phytotoxins in inhibiting the eukaryotic proteasome


Dudler, Robert (2014). The role of bacterial phytotoxins in inhibiting the eukaryotic proteasome. Trends in Microbiology, 22(1):28-35.

Abstract

The ubiquitin-26S proteasome degradation system (UPS) plays a pivotal role in almost all aspects of plant life, including defending against pathogens. Although the proteasome is important for plant immunity, it has been found to be also exploited by pathogens using effectors to increase their virulence. Recent work on the XopJ effector and syringolin A/syrbactins has highlighted host proteasome inhibition as a virulence strategy of pathogens. This review will focus on these recent developments.

Abstract

The ubiquitin-26S proteasome degradation system (UPS) plays a pivotal role in almost all aspects of plant life, including defending against pathogens. Although the proteasome is important for plant immunity, it has been found to be also exploited by pathogens using effectors to increase their virulence. Recent work on the XopJ effector and syringolin A/syrbactins has highlighted host proteasome inhibition as a virulence strategy of pathogens. This review will focus on these recent developments.

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3 citations in Web of Science®
3 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:07 Faculty of Science > Department of Plant and Microbial Biology
Dewey Decimal Classification:580 Plants (Botany)
Language:English
Date:2014
Deposited On:09 Jan 2014 10:15
Last Modified:05 Apr 2016 17:16
Publisher:Elsevier
ISSN:0966-842X
Publisher DOI:https://doi.org/10.1016/j.tim.2013.10.010
PubMed ID:24284310

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